Località: Rozzano, IT, 20089

MRI scientist on the Project “Functional Plasticity in Pain-Related Circuits Upon Brain Radiosurgery in Patients with Refractory Chronic Pain”

We are seeking an MRI scientist to join our project, “Functional plasticity in pain-related circuits upon brain radiosurgery in patients with refractory chronic pain.” We would greatly appreciate your suggestions for potential candidates or sharing this information with those who may be interested.

The project aims to use MRI to investigate functional and structural changes in the brain circuits of patients with intractable and refractory chronic neuropathic pain undergoing thalamus or trigeminal nerve radiosurgery with Gamma Knife. The post-holder will collaborate with our research group to develop MRI acquisition methods, analyze signals, and apply these methods to study the human brain in healthy volunteers and patients with neuropathic pain. The project includes also the integration of human data (including imaging, neuropsychological, and clinical data) with preclinical data.

This position is ideal for researchers with a background in applied physics, engineering, or neuroscience, who are capable of developing a strong understanding of MRI.

The expected start date for this position is January 2025, with some flexibility depending on candidate availability. The project is scheduled to start in January 2025, will last for 3 years, and is based at the IRCCS Humanitas Research Hospital in Rozzano, Italy. The appointment will be within the Neuroradiology Unit directed by Prof. Politi. The unit collaborates closely with the Neurosurgery, Radiotherapy, Neuro-oncology and Neurology Units of the Hospital. A Siemens Naeotom Alpha photon-counting CT and a Siemens 3T Cima.X MRI scanner will be installed by the end of 2024 (September and December 2024, respectively) and will be dedicated to clinical research, and the Unit is currently equipped with a Siemens 3T SkyraFit MRI scanner, four 1.5T scanners, and a 1T MRI scanner. The Unit also has high-performance computing and cloud processing resources. For more information about the unit and its research activities, visit https://www.hunimed.eu/neuroradiology-research-group/.

Compensation will be based on the candidate’s background and level of experience.

Professional Profile and Responsibilities

The selected candidate will:

• Perform processing and analysis of magnetic resonance images;
• Optimize human MRI protocols and assist in acquiring MR images for research studies;
• Conduct MRI quality assurance using phantoms;
• Write articles for scientific publications;
• Contribute to the research projects of the Neuroradiology Research Group.

Required Education

• Master’s degree in physics, biomedical engineering, computer science, neuroscience, or psychology

Technical Skills

• Strong programming skills for image and signal processing and statistical analysis (Python, Matlab, R, etc.);
• Familiarity with common brain imaging analysis toolboxes (FSL, SPM, MRtrix, etc.).

Preferred Qualifications

• PhD in MRI-related topics (MRI image acquisition and processing, pulse programming, etc.);
• Experience with clinical and/or preclinical MRI scanners;
• Experience with the XNAT platform;
• Expertise in diffusion MRI, functional MRI, perfusion MRI, relaxometry, and MR signal modeling;
• Strong scientific track record;
• Highly organized and reliably independent, with attention to detail and an eagerness to acquire new skills.

The notice is addressed to candidates in compliance with Dlgs 198/2006 and Dlgs 215/2003 and 216/2003. Interested persons are invited to read the privacy notice ex art. 13 and 14 of EU Reg. 2016/679.